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Phase 2Data readout

Evorpacept (ALX148) + Trastuzumab + Chemotherapy (CD47 Blocker)

Breast Cancer, Cancer

ALXOALX Oncology Holdings Inc
Expected catalystAugust 15, 2027Company guidance: Aug 15, 2027

Catalyst overview

Event details

Drug or asset
Evorpacept (ALX148) + Trastuzumab + Chemotherapy (CD47 Blocker)
Development stage
Phase 2
Event type
Data readout
Indication
Breast Cancer, Cancer
Research signalsHigh management interest

Research summary

What is being tracked?

This catalyst tracks a Phase 2 data readout for Evorpacept (ALX148) + Trastuzumab + Chemotherapy (CD47 Blocker) in Breast Cancer, Cancer. The expected timing is based on the latest available company guidance and may change.

Development notes

11/07/25:- Phase 2 ASPEN-09 HER2+ breast cancer trial plans FPI in Q4 2025; interim data expected Q3 2026. 01/08/26:- First patient dosed in Ph2 ASPEN-09-Breast; interim data expected Q3 2026. 02/27/26:- ASPEN-09-Breast expanding to 120 patients; primary CD47-high ORR; topline data for 80 patients expected Mid-2027. 05/08/26:- ASPEN-09-Breast enrollment on track; topline data for 80 HER2+ patients still expected Mid-2027. 08/06/26:- ASPEN-09-Breast enrollment remains on track; topline data expected Mid-2027.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

More from ALXO

Related pipeline programs

Phase 1/2

Evorpacept (ALX148) + Zanidatamab

Breast cancer, Cancer

View company pipeline
Phase 1

ALX2004

EGFR-expressing solid tumors

View company pipeline

Company

ALX Oncology Holdings Inc

ALXO · NasdaqGS
Industry
Biotechnology
Pipeline assets
13
View ALXO research

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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
AboutMethodologyTermsPrivacy