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ApprovedUpdate

Vepdegestrant (Mono)

ESR1-Mutated, ER+/HER2- Advanced or Metastatic Breast Cancer

ARVNArvinas Inc.
Expected catalystTBA

Catalyst overview

Event details

Drug or asset
Vepdegestrant (Mono)
Development stage
Approved
Event type
Update
Indication
ESR1-Mutated, ER+/HER2- Advanced or Metastatic Breast Cancer

Research summary

What is being tracked?

This catalyst tracks a Approved update for Vepdegestrant (Mono) in ESR1-Mutated, ER+/HER2- Advanced or Metastatic Breast Cancer. The expected timing is based on the latest available company guidance and may change.

Development notes

VERITAC-2 trial. 3/11/25- Met primary endpoint. Presented Ph3 data at ASCO'25. 8/8/25- NDA accepted. PDUFA date June 5, 2026. 10/20/25- New patient-reported outcomes data at ESMO'25. 11/24/25- Presentation at SABCS'25 on Dec 12th. 02/24/26:- June 5, 2026 PDUFA date reiterated for ESR1-mutated ER+/HER2- advanced breast cancer indication. 05/01/26:- FDA approved Veppanu for ESR1-mutated ER+/HER2- metastatic breast cancer, ahead of June 5, 2026 PDUFA. 05/12/26:- VEPPANU highlighted as first FDA-approved PROTAC; NCCN breast guidelines Category 2A; global rights licensed to Rigel. 08/04/26:- VEPPANU approval, Rigel license, NCCN Category 2A status reiterated.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

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Company

Arvinas Inc.

ARVN · NasdaqGS
Industry
Biotechnology
Pipeline assets
15
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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
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