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Phase 3Update

Barzolvolimab (CDX-0159)

Chronic inducible urticaria

CLDXCelldex Therapeutics, Inc.
Expected catalystTBA

Catalyst overview

Event details

Drug or asset
Barzolvolimab (CDX-0159)
Development stage
Phase 3
Event type
Update
Indication
Chronic inducible urticaria

Research summary

What is being tracked?

This catalyst tracks a Phase 3 update for Barzolvolimab (CDX-0159) in Chronic inducible urticaria. The expected timing is based on the latest available company guidance and may change.

Development notes

7/29/24- Reported topline results. 10/28/24- Met all primary & secondary endpoints. 3/1/25- Presented Ph2 data at AAAAI'25. 11/6/25- New data presented at ACAAI'25. Initiate Ph3 trial in ColdU and SD in December 2025. 11/10/25:- 20-week Ph2 ColdU/SD data positive; OLE data expected Q1 2026; Ph3 initiation planned December 2025. 12/09/25:- Global Phase 3 EMBARQ-ColdU and SD initiated; Phase 2 OLE data expected Q1 2026. 02/23/26:- Phase 2 ColdU/SD study and OLE data to be presented at AAAAI 2026, including late-breaking OLE results. 02/25/26:- Ph3 EMBARQ-ColdU/SD enrollment actively accruing; late-breaking ColdU/SD Ph2 data to be presented March 1, 2026. 03/01/26:- Ph2 ColdU/SD OLE retreatment data positive at AAAAI 2026; Ph3 EMBARQ-ColdU/SD enrolling. 03/27/26:- AAD 2026 posters showed Ph2 ColdU/SD QoL improvements; Ph3 EMBARQ-ColdU/SD enrollment ongoing. 05/07/26:- EMBARQ-ColdU/SD Ph3 trial actively enrolling; prior positive Ph2 efficacy and QoL data reiterated. 07/21/26:- Phase 3 EMBARQ-ColdU/SD enrollment on track; data timing not provided. 08/06/26:- Ph3 EMBARQ-ColdU/SD actively enrolling; no data timing provided.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

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Company

Celldex Therapeutics, Inc.

CLDX · NasdaqCM
Industry
Biotechnology
Pipeline assets
9
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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
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