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Phase 3Data readout

WAKIX® (pitolisant)

Rare genetic disease, Genetic disorder, Prader-Willi syndrome, Excessive daytime sleepiness

HRMYHarmony Biosciences Holdings Inc
Expected catalystAugust 15, 2027Company guidance: Aug 15, 2027

Catalyst overview

Event details

Drug or asset
WAKIX® (pitolisant)
Development stage
Phase 3
Event type
Data readout
Indication
Rare genetic disease, Genetic disorder, Prader-Willi syndrome, Excessive daytime sleepiness

Research summary

What is being tracked?

This catalyst tracks a Phase 3 data readout for WAKIX® (pitolisant) in Rare genetic disease, Genetic disorder, Prader-Willi syndrome, Excessive daytime sleepiness. The expected timing is based on the latest available company guidance and may change.

Development notes

TEMPO study. 11/1/22- Initial Ph2 top-line results. 7/20/23- End-of-Ph2 meeting w/ FDA. Presentation at SLEEP & FPWR '23. 2/20/24- Granted Orphan Drug designation. 4/3/24- Ph3 initiated. 11/04/25:- PR No update. 01/12/26:- TEMPO Ph3 topline data in H2 2026, supporting pediatric exclusivity and additional WAKIX regulatory exclusivity. 02/24/26:- TEMPO Ph3 PWS topline data expected H2 2026, supporting WAKIX pediatric and regulatory exclusivity extension. 05/07/26:- TEMPO PWS Ph3 topline remains expected 2H 2026, supporting WAKIX pediatric exclusivity extension to March 2030. 08/04/26:- TEMPO Ph3 PWS topline expected Mid-2027; PDUFA anticipated 2028.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

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Company

Harmony Biosciences Holdings Inc

HRMY · NasdaqGM
Industry
Biotechnology
Pipeline assets
14
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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
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