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Phase 2Data readout

Darovasertib (IDE196) + crizotinib

Solid tumor/s, Metastatic uveal melanoma, Cancer, Cutaneous Melanoma

IDYAIDEAYA Biosciences
Expected catalystOctober 23, 2026Company guidance: Oct 23, 2026

Catalyst overview

Event details

Drug or asset
Darovasertib (IDE196) + crizotinib
Development stage
Phase 2
Event type
Data readout
Indication
Solid tumor/s, Metastatic uveal melanoma, Cancer, Cutaneous Melanoma
Research signalsHigh management interest

Research summary

What is being tracked?

This catalyst tracks a Phase 2 data readout for Darovasertib (IDE196) + crizotinib in Solid tumor/s, Metastatic uveal melanoma, Cancer, Cutaneous Melanoma. The expected timing is based on the latest available company guidance and may change.

Development notes

IDE196-001 trial. Collab w/ Pfizer. 8/29/25-Present Ph2 Median OS data at SMR in October 25-28, 2025. 11/04/25:- OptimUM-01 Ph2 1L mUM data: 21.1m OS, 7.0m PFS, 34% ORR, 90% DCR, manageable safety. 02/17/26:- OptimUM-01 Phase 2 HLA*A2-positive metastatic uveal melanoma enrollment ~100 patients targeted complete by Q2 2026. 05/05/26:- Completed OptimUM-01 Ph2 HLA*A2-positive mUM enrollment; data from over 85 patients planned H2 2026. 07/17/26:- OptimUM-01 Ph2 results to be presented at ESMO Oct 23-27, 2026. 08/04/26:- OptimUM-01 ESMO update planned October 2026 with ORR, PFS, and OS data.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

More from IDYA

Related pipeline programs

Phase 2/3

Darovasertib (IDE196) + crizotinib

Solid tumor/s, Metastatic uveal melanoma, Cancer

View company pipeline
Phase 2

Darovasertib

Uveal melanoma

View company pipeline
Phase 1/2

IDE397 (MAT2A) + Trodelvy

MTAP-Deletion Urothelial Cancer

View company pipeline
Phase 1

IDE849 (SHR-4849)

Solid tumors

View company pipeline

Company

IDEAYA Biosciences

IDYA · NasdaqGS
Industry
Biotechnology
Pipeline assets
19
View IDYA research

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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
AboutMethodologyTermsPrivacy