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Phase 1/2Data readout

TH103

Neovascular Age-Related Macular Degeneration (nAMD)

KLRSKalaris Therapeutics
Expected catalystJune 30, 2027Company guidance: Jun 30, 2027

Catalyst overview

Event details

Drug or asset
TH103
Development stage
Phase 1/2
Event type
Data readout
Indication
Neovascular Age-Related Macular Degeneration (nAMD)
Research signalsHigh management interest

Research summary

What is being tracked?

This catalyst tracks a Phase 1/2 data readout for TH103 in Neovascular Age-Related Macular Degeneration (nAMD). The expected timing is based on the latest available company guidance and may change.

Development notes

9/15/25- Ph1b/2 MAD study initiated; topline data in H2 2026. Ph1a SAD data in Q4 2025. 11/12/25:- Ph1a data still expected Q4 2025. 12/17/25:- Initial Ph1a SAD data positive with single-dose efficacy. Ph1b/2 preliminary data expected H2 2026. 01/28/26:- Phase 1 SAD data to be presented at Macula Society on February 26, 2026. 03/17/26:- Ph1a SAD data detailed; Ph1b/2 preliminary data now expected H1 2027; plan Ph3 start by YE 2027. 05/12/26:- Patient screening underway in Ph1b/2 MAD; prelim data still expected H1 2027; Ph3 start YE 2027. 06/12/26:- Ph1a SAD data to be presented at CTS 2026 on June 13, 2026. 06/23/26:- Phase 1a data to be presented at ASRS on July 17, 2026. Ph1b/2 enrolling; initial data still H1 2027. 07/17/26:- Expanded Ph1a SAD data positive at ASRS 2026; Ph1b/2 MAD enrollment ongoing; initial data still H1 2027. 08/11/26:- Ph1b/2 dosing continues. Preliminary data H1 2027. Potential Ph3 start YE 2027.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

Company

Kalaris Therapeutics

KLRS · NasdaqGM
Industry
Biotechnology
Pipeline assets
1
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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
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