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Phase 2/3Data readout

Annamycin + Ara-C (Cytarabine)

Acute myeloid leukemia (AML)

MBRXMoleculin Biotech
Expected catalystTBA

Catalyst overview

Event details

Drug or asset
Annamycin + Ara-C (Cytarabine)
Development stage
Phase 2/3
Event type
Data readout
Indication
Acute myeloid leukemia (AML)

Research summary

What is being tracked?

This catalyst tracks a Phase 2/3 data readout for Annamycin + Ara-C (Cytarabine) in Acute myeloid leukemia (AML). The expected timing is based on the latest available company guidance and may change.

Development notes

05/15/26:- 45 enrolled; 40% blinded CRc persists. June unblinding; 90-subject data Q3 2026; Part B H2 2026. 05/21/26:- ASCO poster May 30, 2026 shows pooled cardiac safety; no cardiotoxicity. 05/29/26:- MIRACLE Ph2b/3 unblinding of first 45 remains on track for June 2026. Cleveland Clinic review found no cardiotoxicity. 06/04/26:- 45th subject enrolled; interim 45-subject unblinding remains on track for Mid-2026. 06/30/26:- MIRACLE interim unblinded efficacy favored Annamycin+HiDAC vs control; iDMC recommended continue; Part A 67/90 enrolled. 07/31/26:- MIRACLE blinded CRc 37% (n=62); 90th treated Sep 2026; Part A unblinding Dec 2026–Feb 2027. 08/14/26:- MIRACLE interim data showed higher remission rates and no cardiotoxicity. Part A enrollment will complete in September 2026; 90-subject unblinding will occur December 2026–February 2027. Part B will begin in H1 2027.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

Company

Moleculin Biotech

MBRX · NasdaqCM
Industry
Biotechnology
Pipeline assets
10
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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
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