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ApprovedUpdate

Welireg/Belzutifan (MK-6482) + Keytruda/Pembrolizumab (MK-3475) (HIF-2α/PD-1 Blockade)

Adjuvant Clear Cell Renal Cell Carcinoma After Nephrectomy

MRKMerck & Co
Expected catalystTBA

Catalyst overview

Event details

Drug or asset
Welireg/Belzutifan (MK-6482) + Keytruda/Pembrolizumab (MK-3475) (HIF-2α/PD-1 Blockade)
Development stage
Approved
Event type
Update
Indication
Adjuvant Clear Cell Renal Cell Carcinoma After Nephrectomy

Research summary

What is being tracked?

This catalyst tracks a Approved update for Welireg/Belzutifan (MK-6482) + Keytruda/Pembrolizumab (MK-3475) (HIF-2α/PD-1 Blockade) in Adjuvant Clear Cell Renal Cell Carcinoma After Nephrectomy. The expected timing is based on the latest available company guidance and may change.

Development notes

02/28/26:- LITESPARK-022 interim Phase 3 improved DFS in adjuvant RCC. FDA accepted supplements; PDUFA June 19, 2026. 06/15/26:- FDA approved KEYTRUDA or KEYTRUDA QLEX plus WELIREG for adjuvant ccRCC.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

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Company

Merck & Co

MRK · NYSE
Industry
Biotechnology
Pipeline assets
96
View MRK research

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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
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