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Phase 1Data readout

Micvotabart pelidotin (MICVO, formerly PYX-201)

Cancer, 2L/3L R/M HNSCC [Arms: EGFRi+PD(L)-1-experienced; platinum/PD(L)-1-experienced]

PYXSPyxis Oncology
Expected catalystNovember 15, 2026Company guidance: Nov 15, 2026

Catalyst overview

Event details

Drug or asset
Micvotabart pelidotin (MICVO, formerly PYX-201)
Development stage
Phase 1
Event type
Data readout
Indication
Cancer, 2L/3L R/M HNSCC [Arms: EGFRi+PD(L)-1-experienced; platinum/PD(L)-1-experienced]

Research summary

What is being tracked?

This catalyst tracks a Phase 1 data readout for Micvotabart pelidotin (MICVO, formerly PYX-201) in Cancer, 2L/3L R/M HNSCC [Arms: EGFRi+PD(L)-1-experienced; platinum/PD(L)-1-experienced]. The expected timing is based on the latest available company guidance and may change.

Development notes

PYX-201-101 trial. 11/3/25- Preliminary clinical data in Q4 2025. 11/03/25:- Q4 25 prelim mono Ph1 data 12/18/25:- New Ph1 monotherapy data in 2L+ R/M HNSCC; updated durability data planned Mid-2026. 03/23/26:- Ph1 mono expansion enrollment completed; updated 2L+ HNSCC data mid-2026; preclinical maMICVO AACR 2026 data upcoming. 05/14/26:- Mid-2026 MICVO monotherapy Ph1 2L+ R/M HNSCC update on track; AACR 2026 maMICVO combo data presented. 08/13/26:- Phase 1 PYX-201-101 monotherapy data in 2L+ R/M HNSCC will be reported in Fall 2026.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

More from PYXS

Related pipeline programs

Phase 1/2

Micvotabart pelidotin (MICVO, formerly PYX-201) + KEYTRUDA® (pembrolizumab)

Advanced Solid Tumors (various)

View company pipeline

Company

Pyxis Oncology

PYXS · NasdaqGS
Industry
Biotechnology
Pipeline assets
3
View PYXS research

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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
AboutMethodologyTermsPrivacy