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Phase 2Data readout

SPY001 (α4β7)

Crohns disease, Inflammatory bowel disease

SYRESpyre Therapeutics Inc
Expected catalystDecember 31, 2027Company guidance: Dec 31, 2027

Catalyst overview

Event details

Drug or asset
SPY001 (α4β7)
Development stage
Phase 2
Event type
Data readout
Indication
Crohns disease, Inflammatory bowel disease

Research summary

What is being tracked?

This catalyst tracks a Phase 2 data readout for SPY001 (α4β7) in Crohns disease, Inflammatory bowel disease. The expected timing is based on the latest available company guidance and may change.

Development notes

03/16/26:- SKYLINE UC platform enrolling ahead of schedule; Part A readouts begin Q2 2026. 04/13/26:- Positive 12-week Phase 2 SKYLINE Part A data. Part A recruitment closed; Part B enrolling; induction data 2027. 05/05/26:- SPY001 SKYLINE Part A topline showed strong histologic, remission, endoscopic responses; safety consistent. Part B induction data 2027. 08/04/26:- SKYLINE SPY001 data detailed; Part B induction data expected 2027.

Verification

Primary source

Confirm timing and program details against the company announcement or filing.

Open source

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Company

Spyre Therapeutics Inc

SYRE · NasdaqGS
Industry
Biotechnology
Pipeline assets
6
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Updated Aug 23, 2026. Dates can change; this is not investment advice.

Disclaimer: Biotech Stock Intel is an independent research platform. Information is provided for informational purposes only and is not investment or medical advice. Always verify catalyst dates against primary sources and conduct your own research.
Biotech Stock Intel© 2026 Biotech Stock Intel
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