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Clinical portfolio
| Asset | Indication | Stage | Milestone | Signals ? |
|---|---|---|---|---|
| Zipalertinib | Non-small cell lung carcinoma (NSCLC) with EGFR Exon 20 Insertion Mutations | PDUFA | Feb 27, 2027 | Big moverMgmt interestHedge fund pick |
| Zipalertinib | Non-small cell lung carcinoma (NSCLC) | Phase 3 | Sep 14, 2026 | — |
| Velinotamig (BCMAxCD3) (T Cell Engager) | Autoimmune Diseases | Phase 1/2 | Dec 31, 2026 | — |
Upcoming milestones
Company profile
Cullinan Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops therapies for autoimmune diseases and cancer in the United States. It engages in the development of CLN-978, a CD19xCD3 bispecific T cell engager for autoimmune diseases in Phase 1 clinical trials; Velinotamig, a BCMAxCD3 bispecific T cell in Phase 1 clinical trials in patients with autoimmune diseases; and CLN-049, a FLT3xCD3 bispecific T cell engager, which is in Phase 1 clinical trials in patients with relapsed and refractory acute myeloid leukemia or myelodysplastic syndrome. The company is also developing Zipalertinib, an orally available small-molecule, irreversible epidermal growth factor receptor inhibitor in Phase 2b portion of the REZILIENT1 clinical trial in patients with EGFR ex20ins non-small cell lung cancer. It has a license agreement with Chongqing Genrix Biopharmaceutical Co., Ltd to develop and commercialize velinotamig; a co-development agreement with Taiho Pharmaceutical Co., Ltd to develop zipalertinib; and a collaboration agreement with Adimab, LLC to discover and/or optimize antibodies. The company was formerly known as Cullinan Oncology, Inc. and changed its name to Cullinan Therapeutics, Inc. in April 2024. Cullinan Therapeutics, Inc. was incorporated in 2016 and is headquartered in Cambridge, Massachusetts.
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Non-small cell lung carcinoma (NSCLC)
Data readoutRheumatoid Arthritis
Data readout