Systemic Lupus Erythematosus
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Clinical portfolio
| Asset | Indication | Stage | Milestone | Signals ? |
|---|---|---|---|---|
| Claseprubart (DNTH103) | Generalized Myasthenia Gravis (gMG) | Phase 3 | Dec 31, 2028 | — |
| Claseprubart (DNTH103) | Multifocal Motor Neuropathy (MMN) | Phase 2 | Dec 31, 2026 | Mgmt interest |
| LBL-047 (DNTH212) (BDCA2/TACI Inhibitor) | Systemic Lupus Erythematosus | Phase 1 | Dec 31, 2026 | Mgmt interest |
Upcoming milestones
Company profile
Dianthus Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of therapies for patients with severe autoimmune diseases. Its lead clinical-stage candidate, claseprubart, a monoclonal antibody engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein; and DNTH212, a bifunctional fusion protein that targets plasmacytoid dendritic cell (pDC) BDCA2 to reduce Type 1 interferon production, while simultaneously inhibiting BAFF/APRIL to suppress B cell function. Dianthus Therapeutics, Inc. was founded in 2019 and is headquartered in New York, New York.
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Multifocal Motor Neuropathy (MMN)
Data readoutSystemic Lupus Erythematosus
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